Biorbyt's HIST1H3 antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The HIST1H3 antibody was generated using H3 clustered histone 1, H3 clustered histone 10, H3 clustered histone 11, H3 clustered histone 12, H3 clustered histone 2, H3 clustered histone 3, H3 clustered histone 4, H3 clustered histone 6, H3 clustered histone 7, H3 clustered histone 8, H3C1, H3C10, H3C11, H3C12, H3C2, H3C3, H3C4, H3C6, H3C7, and H3C8 as the antigen and it reacts with Homo Sapiens, Human, and Mouse.
Description
Rabbit polyclonal to HIST1H3. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling